Our intensive care units (ITU) are research active with opportunities to get involved.

AIRWAYS-3

The AIRWAYS-3 study is looking to find the best way to keep a patient’s airway open so artificial breathing can be given during a cardiac arrest. It is comparing two methods currently used routinely in NHS care.

e-PICS

The e-PICS study is looking to find out more about PICS (Post Intensive Care Syndrome) symptoms that patients experience during their first few months after going home from an ICU or high-dependency unit (HDU) stay. Monitoring these symptoms could help us identify patient rehabilitation needs earlier, so we can support patients better with their critical illness recovery.

This is a PhD study, for further information please contact the Critical Care research team.

GenOMICC

the GenOMICC study looks at the DNA of people who are critically ill and need ITU/HDU (High Dependency) care. Some of our genes (or DNA) affect how vulnerable we are to critical illness, and this study is trying to find these genes because they could help develop better treatments for other patients in the future.

GuARDS

The GuARDS study is looking to answer if dexamethasone treatment in patients with ARDS can save lives, reduce the need for extended ICU care, improve longer term patient quality of life and find the best value for the public and health services.

MOSAICC

the MOSAICC study is looking at the effect of administrating sodium bicarbonate to critically ill patients with acute kidney injury and a metabolic acidosis compared with usual treatment including renal replacement therapy.

REMAP-CAP

The REMAP-CAP trial looks at the treatment for community-acquired pneumonia (CAP) in ITU patients. This is an adaptive trial which also has treatment domains for patients who have flu or COVID-19.

SIGNET

The SIGNET study will evaluate the benefits of a single dose of simvastatin given to potential organ donors to understand if the level of inflammation following the transplant can improve outcomes for the organ recipient.

How to get involved

Our Critical Care Research team cover three specialties: the Emergency Department (ED); anaesthetics, peri-operative, medicine and pain (APOMP) and intensive care (ITU), and have a successful portfolio of studies.

If you are interested in participating in research and would like some more information about the studies we are supporting, contact the Critical Care Research team at mtw-tr.criticalcare-research@nhs.net.